Iodine and cancer relationship 2013

iodine and cancer relationship 2013

PDF | Thyroid cancer (TC) is the most common malignancy of the endocrine system. We aim to figure out the relationship between iodine intake and TC Tian () Case–control Dalian, China Case n=65 Saltwater fish. 0. June 29, Available in: English Iodine actually induces apoptosis as well, meaning it causes cancer cells to self-destruct. Dr. Jorge Flechas, MD is. The molecular effects of iodine as well as ongoing epidemiological evidence The link between gastric cancers and areas of endemic goiter dates back to .

A higher intake of dietary iodine was as a protective factor for TC. However, the available data are very limited and more studies are required. Introduction Thyroid cancer TC is the most common malignancy of the endocrine system.

There is a U-shaped relationship between iodine intake and thyroid disease, indicating that either too much or too little iodine intake will lead to thyroid diseases.

Urinary Iodine Concentrations in Cancer Patients

For example, a higher dietary iodine intake has, in fact, been shown to significantly decrease the risk of TC. Therefore, we performed current meta-analysis of all available epidemiological studies to provide a comprehensive estimate of the possible relationship between iodine intake and TC risk.

Materials and methods This study is a meta-analysis and ethics statement is not applicable. In addition, the reference lists of relevant articles were searched to identify additional relevant papers.

Inclusion and exclusion criteria The inclusion criteria included: Observed association between improved iodine supply and decrease of incidence of stomach cancer could indicate the protective role against stomach cancer of iodine prophylaxis in iodine deficient areas. In the stomach, iodine protects against abnormal growth of bacteria, in which Helicobacter pylori is the most clinically significant.

Iodine in the stomach can also deactivate all biological and most chemical poisons Stadel Failure to trigger the apoptosis in gastric cancer cells resulting from decreased iodine might be harmful Gulaboglu et al, Zhang et al have shown that increased intracellular levels of iodine is associated with enhance tumor apoptosis in most of the modified non-small cell lung cancer.

They assessed a nonradioactive approach in the non-small cell lung cancer with retroviral vectors containing NIS and thyroperoxidase TPO genes. They for first time demonstrated that a therapeutic dose of nonradioactive iodide has potent efficacy and high selectivity against lung cancer Zhuang et al, An increased risk of thyroid cancer has been reported in humans with goiter and those living in some iodine-deficient areas of the world Ohshima et al, Studies suggest that a major role of iodine is to prevent the formation of thyroid tumors in humans Ward et al.

Iodine deficiency is also associated with increased risk for thyroid carcinoma in animal models. Mutaku JF and et al have shown anti-proliferative effects of excess iodine on thyroid cells Mutaku et al, To the best of our knowledge this was the first study evaluated the iodine status in Iranian patients diagnosed with a malignancy.

However, results of the present study showed severe iodine deficiency in the patients. Therefore, check the status of iodine in normal populations and cancer patients may be crucial. In addition, we suggest that daily consumption of salt fortified with iodine or other approaches might be an effective strategy for prevention or reduction of malignancies.

The Extrathyronine actions of Iodine as antioxidant, apoptotic, and differentiation factor in various tissues. East Mediterr Health J. Medical Alternative Press; Sodium Iodide symporter and the radioiodine treatment of thyroid carcinoma.

Nucl Med Mol Imaging. Government Dietary Recommendations January 7th may also have impact since reduction in dietary salt intake from 3, to 2, mg per day may further reduce the intake of iodine from iodized salt.

iodine and cancer relationship 2013

Such recommendations for universal salt restriction i. In conclusion, dietary iodine insufficiency represents a plausible explanation for the increasing incidence of breast cancer in young women with distant metastasis.

Iodine and relax-sakura.info they are not telling you!!!!

In view of the established reduction in iodine levels in US women of childbearing age since the mid 70s, this group would be most vulnerable to increased breast cancer risk. The increased sensitivity of breast tissue to estradiol induced proliferative changes in the setting of dietary iodine insufficiency, provides a plausible mechanistic explanation for the increasing incidence of breast cancer with distant involvement in this age group.

Based on the importance of iodine in thyroid and breast health, fetal brain development, as well as deficits in nutritional trends among younger women, iodine testing and management may be considered as a potentially important aspect for clinical practice.

Competing Interests The author has declared that no competing interest exists. Incidence of breast cancer with distant involvement among women in the United States, to Incidence rate of breast cancer in young women.

Radioactive Iodine for Overactive Thyroid and Breast Cancer Link | Cancer Chat

Hou N, Huo D. Goldstein MR, Mascitelli L. Incidence rate of breast cancer in young women-reply. Iodine metabolism and breast cancer.

iodine and cancer relationship 2013

Trans N Y Acad Sci. Dietary iodine and risk of breast, endometrial, and ovarian cancer.

Urinary Iodine Concentrations in Cancer Patients

Estimates of the worldwide incidence of 25 major cancers in Breast cancer survival among Hawaii Japanese and Caucasian women. Ten-year rates and survival by place of birth.

Trends in the incidence of female breast and cervical cancers in Miyagi Prefecture, Japan, Jpn J Cancer Res. Is iodine a gatekeeper of the integrity of the mammary gland?. J Mammary Gland Biol Neoplasia. The extrathyronine actions of iodine as antioxidant, apoptotic, and differentiation factor in various tissues.

Radioactive Iodine for Overactive Thyroid and Breast Cancer Link

Thyroid disease in patients with benign and malignant mastopathy. Breast cancer in association with thyroid disorders. A direct relationship between thyroid enlargement and breast cancer. J Clin Endocrinol Metab. Thyroid diseases and breast cancer. Thyroid disorders and breast cancer.

Eur J Cancer Prev.